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Simcha Srebnik

Associate Professor

Research Fields

Molecular simulation and theory of polymers
Molecular imprinting technology
Carbon nanotube-polymer composites
Membrane separations

Research Topics

Molecular simulation and theory of polymers
Today’s era of nanoscience and technology challenges researchers to focus on material behavior and characterization at the molecular level. The goal of our research is the utilization and development of molecular simulation and theory to characterize polymer-based systems for applications in nano†and biotechnology. Our modeling techniques involve various types of atomistic and coarseâ€grained simulations, probing the molecular structure and dynamics of materials and its relation to material behavior.
Carbon Nanotube – Polymer Composites
Carbon nanotubes were discovered in the early 1990’s and since then have been vastly researched due to their extraordinary mechanical, electronic, and thermal properties. The addition of a small amount of nanotubes to polymeric (and ceramic) materials has shown to greatly reinforce the required material properties. Applications of such composites include flame retardants for plastics and photovoltaic cells. Our research focuses on the CNTâ€polymer interface and its influence on the properties of the composite.
Molecular Imprinting
Molecular imprinting technology is used to synthesize polymer gels with biomimetic properties. That is, like biological molecules, these synthetic gels are able to recognize a specific molecule of interest. Applications of this technology include separations, sensors, and controlled drug release. In the case of molecular imprinting of proteins, the most aspired application is to create selective proteinâ€binding assays as synthetic antibodies. However, while imprinting of small molecules has been successfully achieved for a number of species and has even been applied to separation of enantiomers, imprinting proteins has proven to be much more difficult. Our research aims at optimizing proteinâ€imprinting technology through molecularâ€level understanding of the imprinting process. We perform simulations on various levels to understand the relation between the complex nature of proteins and the selectivity of the imprinted material.
Interfacial Polymerization
Interfacial polymerization is widely used today for the production of ultrathin (


Ravit Edelman, Iliya Kusner, Renata Kisiliak, Simcha Srebnik, and Yoav D. Livney. Templating Effect of Sugars on Water Structure and on Protein Stability, Food Hydrocolloids, 48 (2015) 27-37.

O. Kucher, I. Yungerman, and S. Srebnik, Coarse-grained model for sequence-dependent adsorption of ssDNA on carbon nanotubes, Journal of Physical Chemistry C, 18 (2014) 17677.

Moskovitz Y. and Srebnik S., Conformational changes of globular proteins upon adsorption on a hydrophobic surface, Physical Chemistry Chemical Physics, 16 (2014) 11698.

L. Levi, V. Raim, and S. Srebnik, A brief review of theoretical and computational studies of molecular imprinting, Journal of Molecular Recognition, 24 (2011) 883.

Srebnik S. and Douglas J.F., Self-assembly of charged particles on nanotubes and the emergence of particle rings, chains, ribbons and chiral sheets, Soft Matter, 7 (2011) 6897.

R. Oizerovich-Honig, V. Raim, and S. Srebnik, Simulation of thin film membranes formed by interfacial polymerization, Langmuir, 26 (2010) 299.

I. Gurevitch and S. Srebnik, Conformational behavior of polymers adsorbed on nanotubes, Journal of Chemical Physics, v. 128, 144901, 2008.

I. Yungerman and S. Srebnik, Factors contributing to pore imperfections in imprinted polymers, Chemistry of Materials, v. 18, 657-663, 2006.